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Using Steered Molecular Dynamics to Predict and Assess Hsp70 Substrate-Binding Domain Mutants that Alter Prion Propagation 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2013, 卷号: 9, 期号: 1, 页码: -
Authors:  Xu, Linan;  Hasin, Naushaba;  Shen, Manli;  He, Jianwei;  Xue, Youlin;  Zhou, Xiaohong;  Perrett, Sarah;  Ke S(柯莎);  Song, Youtao;  Jones, Gary W;  XU LN
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Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2 期刊论文
Authors:  Xu, LiQiong;  Wu, Si;  Buell, Alexander K;  Cohen, Samuel I A;  Chen, LiJun;  Hu, WanHui;  Cusack, Sarah A;  Itzhaki, Laura S;  Zhang, hong;  Zhang H(张宏);  Knowles, Tuomas P J;  Dobson, Christopher M;  Welland, Mark E;  Jones, Gary W;  Perrett, Sarah;  Ke S(柯莎)
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Prion  Amyloid  Ure2p  Ssa1p  Chaperone  Quartz Crystal Microbalance  
Relationship between Prion Propensity and the Rates of Individual Molecular Steps of Fibril Assembly 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 卷号: 286, 期号: 14, 页码: -
Authors:  Wang, YiQian;  Buell, Alexander K;  Wang, XinYu;  Welland, Mark E;  Dobson, Christopher M;  Knowles, Tuomas P J;  Perrett, Sarah;  Ke S(柯莎);  KNOWLES TPJ
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The yeast prion protein Ure2: insights into the mechanism of amyloid formation 期刊论文
BIOCHEMICAL SOCIETY TRANSACTIONS, 2011, 卷号: 39, 页码: 1359-1364
Authors:  Chen, LiJun;  Sawyer, Elizabeth B;  Perrett, Sarah;  Ke S(柯莎)
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Amyloid  Chaperone  Prion  Saccharomyces Cerevisiae  Ure2p  [Ure3]  
Flexibility of the Ure2 prion domain is important for amyloid fibril formation 期刊论文
BIOCHEMICAL JOURNAL, 2011, 卷号: 434, 页码: 143-151
Authors:  Yu, Yong;  Wang, HaiYan;  Bai, Ming;  Perrett, Sarah;  Ke S(柯莎)
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Amyloid  Mutant  Protein Folding  Sequence Permutation  Ure2p  Yeast  
Deletion of a Ure2 C-terminal prion-inhibiting region promotes the rate of fibril seed formation and alters interaction with Hsp40 期刊论文
PROTEIN ENGINEERING DESIGN & SELECTION, 2011, 卷号: 24, 期号: 1-2, 页码: 69-78
Authors:  Chen, Li;  Chen, LiJun;  Wang, HaiYan;  Wang, YiQian;  Perrett, Sarah;  Ke S(柯莎)
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Amyloid  Folding  Prion  Ure2p  [Ure3]  
The fibrils of Ure2p homologs from Saccharomyces cerevisiae and Saccharoymyces paradoxus have similar cross-beta structure in both dried and hydrated forms 期刊论文
JOURNAL OF STRUCTURAL BIOLOGY, 2011, 卷号: 174, 期号: 3, 页码: 505-511
Authors:  Wang, YiQian;  Bongiovanni, Marie;  Gras, Sally L;  Perrett, Sarah;  Ke S(柯莎);  GRAS SL
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Yeast  Prion  Amyloid  Ure2  [Ure3]  X-ray Fiber Diffraction  
New insights into the molecular mechanism of amyloid formation from cysteine scanning 期刊论文
PRION, 2010, 卷号: 4, 期号: 1, 页码: 9-12
Authors:  Fei, Li;  Perrett, Sarah;  Ke S(柯莎)
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Yeast  Prion  Amyloid  Cysteine Scanning  Disulphide Bond  Ure2  Ure2p  Peptide  Crystal  Initiation Site  
Amyloid-Like Aggregates of the Yeast Prion Protein Ure2 Enter Vertebrate Cells by Specific Endocytotic Pathways and Induce Apoptosis 期刊论文
PLOS ONE, 2010, 卷号: 5, 期号: 9, 页码: -
Authors:  Zhang, Chen;  Jackson, Antony P;  Zhang, ZaiRong;  Han, Yan;  Yu, Shun;  He, Rongqiao;  He RQ(赫荣乔);  Perrett, Sarah;  Ke S(柯莎)
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Novel Glutaredoxin Activity of the Yeast Prion Protein Ure2 Reveals a Native-like Dimer within Fibrils 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 卷号: 284, 期号: 21, 页码: 14058-14067
Authors:  Zhang, ZaiRong;  Perrett, Sarah;  Ke S(柯莎)
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